BCM-95® (CURCUGREEN®), 06 Aug 2021

Synofit Premium in Refractory Low Back Pain: A Retrospective Observational Study

Jiangan Qu, Christian Mélot, Thierry Appelboom

Doi: 10.4236/ojra.2017.72011

Introduction: In this retrospective observational study, information about pain and quality of life was collected for analysis from medical records of 85 patients with chronic low back pain who were treated for 3 months with Synofit® Premium (2 – 3 capsules daily), a liquid mixture of green-lipped mussel from New Zealand, blackcurrant leaf, and curcuma extract.

Observation: Within the first 6 weeks of therapy, a significant clinical benefit was observed for relief from pain, need for pain-relieving drugs, and the interference of pain with personal care and lifting. This benefit was more pronounced at 3 months. The mixture was well tolerated without significant side effects. Adherence was estimated to be “good” to “very good.” Patients assessed global improvement and efficacy as “sufficient” to “good.”

Result: Based on this study, the mode of action of Synofit® Premium appears mainly to be analgesic, as reported by patients, and allows them to reduce the consumption of other pain-relieving substances and improve their quality of life.

Conclusion: In conclusion, Synofit® Premium holds potential as a promising candidate alternative therapy for relief of low back pain and likely other painful rheumatic conditions, with almost no or minor side effects.



  • Blackcurrant Leaf
  • Curcuma longa
  • Curcumin
  • Low Back Pain
  • osteoarthritis
  • Perna canaliculus
  • Ribes nigrum
  • Synofit

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Arjuna Natural is India’s leading manufacturer and exporter of standardized botanical extracts for pharmaceutical and nutraceutical industries for more than two decades. Established in 1989, the company has grown...Read More

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