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Verapamil/Curcumin treatment attenuates the behavioral alterations observed in Williams Syndrome mice by regulation of MAPK pathway and Microglia overexpression.

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Paula Ortiz-Romero, Gustavo Egea, Luis A Pérez-Jurado, Victoria Campuzano The study investigated the progression of behavioral deficits present in CD (complete deletion) mice, a rodent model of Williams-Beuren syndrome (WBS), a rare neurodevelopmental disorder without any effective treatments.  The test compounds curcumin, verapamil and a combination of both were given as chronic treatments. These compounds have ... Read full Research

The benefit of Curcuma longa and Boswellia serrata to improve quality of life in osteoarthritis patients: a randomized controlled trial.

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Background: Quality of life (QoL) can be affected by chronic pain in osteoarthritis (OA). Previous studies showed that combination of Curcuma longa (CL) and Boswellia serrata (BS) extract (CB extract) are promising foralternative treatment for pain in OA. This study aimed to measure the benefit of CB extract to improve QoL in patients with OA. ... Read full Research

A Randomized Controlled Trial of Curcuma Longa and Boswellia Serrata Extract in Osteoarthritis.

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Rizaldy Taslim Pinzon, Rosa De Lima Renita Sanyasi, Esdras Ardi Pramudita& Septian Dewi Periska Chronic pain is the major complaint in subjects with osteoarthritis (OA). Non- steroid anti inflammatory drug (NSAID) is still the drug of choice in Indonesia to treat OA patients. The prolonged consumption of NSAID may lead to many adverse events (AE). ... Read full Research

Potential Therapeutic Effects of Curcuma longa extract in Patients with Osteoarthritis: A Randomized Controlled Trial.

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[Rizaldy Taslim Pinzon, Fransiscus Buwana; Potential Therapeutic Effects of Curcuma longa extract in Patients with Osteoarthritis: A Randomized Controlled Trial; J. Pharm. Sci. & Res. Vol. 11(11), 2019, 3628-3633] Osteoarthritis (OA) is the most common degenerative joint disorder in the elderly and a major public health problem in worldwide. Non-steroidal anti-inflammatory drug (NSAID) is a ... Read full Research

Antidiabetic effect of bio-enhanced preparation of turmeric in streptozotocin-nicotinamide induced type 2 diabetic Wistar rats.

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[Vinay Kumar Sayeli, Ashok K. Shenoy; doi.org/10.1016/j.jaim.2021.04.010] Poor oral bioavailability of curcumin, the active ingredient in turmeric, has limited its therapeutic use in various diseases including diabetes mellitus (DM). The present study was aimed at evaluating and comparing the antidiabetic activity as well as pharmacokinetic profile of two turmeric extracts. Rats were divided into seven ... Read full Research

Curcuma longa and Boswellia Serrata for improving functional status in osteoarthritis patients: From bench to bedside evidences.

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[Rizaldy Taslim Pinzon, Vincent Ongko Wijaya; DOI: 10.3126/ajms.v10i5.24918] The management of osteoarthritis (OA) represents a real challenge. Curcumin is a highly pleiotropic molecule with an excellent safety profile. Some previous studies showed the extract of Curcuma longa and Boswellia Serrata(CB extract) is a promising potential as therapeutic interventions against OA. This study aimed to measure ... Read full Research

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Arjuna Naturals

Arjuna Natural Ltd is India’s leading manufacturer and exporter of standardized botanical extracts for pharmaceutical and nutraceutical industries for more than two decades. Established in 1989, the company has grown...Read More

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